Activation of NF- B is a critical element in the antiapoptotic effect of anesthetic preconditioning
نویسندگان
چکیده
Xiyuan Lu, Hong Liu, Lianguo Wang, and Saul Schaefer Departments of Internal Medicine, Division of Cardiovascular Medicine, and Anesthesiology and Pain Management, University of California, Davis; and Cardiology Section, Department of Veteran Affairs, Northern California Health Care System, Mather, California; and Department of Anesthesiology and Pain Medicine, University of Alberta, Edmonton, Alberta, Canada
منابع مشابه
Activation of NF-kappaB is a critical element in the antiapoptotic effect of anesthetic preconditioning.
Anesthetic preconditioning (APC), defined as brief exposure to inhalational anesthetics before cardiac ischemia-reperfusion (I/R), limits injury in both animal models and in humans. APC can result in the production of reactive oxygen species (ROS), and prior work has shown that APC can modify activation of NF-kappaB during I/R, with consequent reduction in the expression of inflammatory mediato...
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تاریخ انتشار 2009